脂肪燃焼促進作用を示す新規へパトカイン：アクチビンE
橋本 統、舟場正幸、栗崎 晃
医学のあゆみ 271(11) 1231-1232 (2019)
Sekiyama K., Ushiro U., Kurisaki A., Funaba M., Hashimoto O. Activin E enhances insulin sensitivity andthermogenesis by activating brown/beige adipocytes. J. Vet.Med. Sci.81(5): 646–652(2019)
SugiyamaM., Shindo D., Kanada N., Ohzeki T., Yoshioka K., Funaba M., Hashimoto O.Inducible brown/beige adipocytes in retro-orbital adipose tissues. Exp. Eye Res. 184: 8–14 (2019)
HashimotoO., FunabaM., Sekiyama K., Doi S, Shindo D., Sato R., Itoi H., Oiwa H., Morita M., SuzukiC., Sugiyama M., Yamakawa N., Takada H, Matsumura S., Inoue K., Oyadomari S., Sugino H., Kurisaki A. Activin E controlsenergy homeostasis in both brown and white adipose tissues as a hepatokine. Cell Rep. 25 (5): 1193–1203 (2018)
Hashimoto O., Noda T., Morita A., Morita M.,Ohtsuki H., SugiyamaM., Funaba M. Castrationinduced browning in subcutaneous white adipose tissue in male mice. Biochem. Biophys. Res. Commun.478 (4): 1746–1750 (2016)
Hashimoto O., Ohtsuki H., Kakizaki T., Amou K., Sato R., Doi S.,Kobayashi S., Matsuda A., Sugiyama M., Funaba M., Matsuishi T., Terasawa F.,Shindo J., Endo H. Brown adipose tissue in cetacean blubber. PLoS One 10: e0116734 (2015)
Hashimoto O., Takagi R., Yanuma F., Doi S., Shindo J., Endo H.,Hasegawa Y., Shimasaki S. Identification andcharacterization of canine growth differentiation factor-9 and its splicingvariant. Gene 499 (2): 266–272 (2012)
Hashimoto O, Funaba M. Activin in Glucose Metabolism.“Vitamins and Hormones, Vol. 85: Activin and Inhibin”, (Ed : G. Litwack),Academic Press, Burlington, pp. 217-234. (2011)
HashimotoO., UshiroY., Sekiyama K., Yamaguchi O., Yoshioka K., Mutoh K., Hasegawa Y. Impairedgrowth of pancreatic exocrine cells in transgenic mice expressing human activinβE subunit. Biochem. Biophys. Res.Commun. 341 (2): 416-424 (2006)
HashimotoO., MooreR. K., Shimasaki S. Post-translational processing of mouse and human BMP-15:potential implication in the determination of ovulation quota. Proc. Natl. Acad. Sci. U. S. A. 102(15): 5426–5431(2005)
HashimotoO.,Kawasaki N., Tsuchida K., Shimasaki S., Hayakawa T., Sugino H. Differencebetween follistatin isoforms in the inhibition of activin signalling: Activinneutralizing activity of follistatin isoforms is dependent on their affinityfor activin. Cell. Signal. 12 (8): 565–571 (2000)
Hashimoto O.,Nakamura T., Shoji H., Shimasaki S., Hayashi Y., Sugino H. A novel role offollistatin, an activin-binding protein, in inhibition of activin action in ratpituitary cells: endocytotic degradation of activin and its acceleration byfollistatin associated with cell-surface heparan sulfate. J. Biol. Chem. 272 (21): 13835–13842 (1997)
