{"id":157,"date":"2015-12-10T16:18:52","date_gmt":"2015-12-10T07:18:52","guid":{"rendered":"http:\/\/b-lab.nagahama-i-bio.ac.jp\/~m_shionyu\/?page_id=157"},"modified":"2015-12-10T16:20:58","modified_gmt":"2015-12-10T07:20:58","slug":"c%e8%a8%80%e8%aa%9e%e8%ac%9b%e5%ba%a7%e3%80%80%e7%ac%ac%ef%bc%99%e5%9b%9e","status":"publish","type":"page","link":"https:\/\/b-lab.nagahama-i-bio.ac.jp\/~m_shionyu\/?page_id=157","title":{"rendered":"C\u8a00\u8a9e\u8b1b\u5ea7\u3000\u7b2c\uff19\u56de"},"content":{"rendered":"

hydropathy plot<\/h2>\n

\u4eca\u56de\u4f5c\u6210\u3059\u308b\u30d7\u30ed\u30b0\u30e9\u30e0\u306f\u3001\u819c\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u819c\u8cab\u901a\u90e8\u4f4d\u3092\u4e88\u6e2c\u3059\u308b\u305f\u3081\u306ehydropathy plot\u3067\u3059\u3002<\/p>\n

\u819c\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u304a\u3044\u3066\u819c\u306b\u57cb\u307e\u3063\u3066\u3044\u308b\u90e8\u4f4d\u306f\u3001\u305d\u306e\u758e\u6c34\u7684\u306a\u74b0\u5883\u306b\u5408\u308f\u305b\u3066\u758e\u6c34\u6027\u306e\u9ad8\u3044\u30a2\u30df\u30ce\u9178\u6b8b\u57fa\u304c\u9577\u304f\u9023\u7d9a\u3057\u3066\u5b58\u5728\u3057\u3066\u3044\u307e\u3059\u3002Kyte & Doolittle\u306b\u3088\u308ahydropathy index\u304c\u4f5c\u6210\u3055\u308c\uff08Kyte J & Doolittle RF, 1982, J Mol Biol, 157:105-132.\uff09\u3001\u5404\u30a2\u30df\u30ce\u9178\u306e\u758e\u6c34\u6027\u304c\u5b9a\u91cf\u7684\u306b\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u306a\u304a\u3001hydropathy index\u306f\u5024\u304c\u5927\u304d\u304f\u306a\u308b\u307b\u3069\u758e\u6c34\u7684\u306a\u30a2\u30df\u30ce\u9178\u3092\u793a\u3057\u3001\u5177\u4f53\u7684\u306a\u6570\u5024\u306f\u4ee5\u4e0b\u306e\u8868\u306e\u901a\u308a\u3067\u3059\u3002<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
residue<\/th>\nindex<\/th>\nresidue<\/th>\nindex<\/th>\n<\/tr>\n
Ile<\/td>\n4.5<\/td>\nTrp<\/td>\n-0.9<\/td>\n<\/tr>\n
Val<\/td>\n4.2<\/td>\nTyr<\/td>\n-1.3<\/td>\n<\/tr>\n
Leu<\/td>\n3.8<\/td>\nPro<\/td>\n-1.6<\/td>\n<\/tr>\n
Phe<\/td>\n2.8<\/td>\nHis<\/td>\n-3.2<\/td>\n<\/tr>\n
Cys<\/td>\n2.5<\/td>\nGlu<\/td>\n-3.5<\/td>\n<\/tr>\n
Met<\/td>\n1.9<\/td>\nGln<\/td>\n-3.5<\/td>\n<\/tr>\n
Ala<\/td>\n1.8<\/td>\nAsp<\/td>\n-3.5<\/td>\n<\/tr>\n
Gly<\/td>\n-0.4<\/td>\nAsn<\/td>\n-3.5<\/td>\n<\/tr>\n
Thr<\/td>\n-0.7<\/td>\nLys<\/td>\n-3.9<\/td>\n<\/tr>\n
Ser<\/td>\n-0.8<\/td>\nArg<\/td>\n-4.5<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

hydropathy index\u3092\u7528\u3044\u3066\u3001\u819c\u8cab\u901a\u90e8\u4f4d\u306f\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u8003\u3048\u65b9\u3067\u6c42\u3081\u307e\u3059\u3002\u3053\u306e\u8003\u3048\u65b9\u306e\u809d\u306f\u3001\uff11\u3064\u306e\u30a2\u30df\u30ce\u9178\u6b8b\u57fa\u3060\u3051\u306e\u758e\u6c34\u6027\u3092\u898b\u308b\u306e\u3067\u306f\u306a\u304f\u3001\u524d\u5f8c\u306e\u30a2\u30df\u30ce\u9178\u6b8b\u57fa\u306e\u758e\u6c34\u6027\u3082\u8003\u616e\u306b\u5165\u308c\u308b\u3068\u3053\u308d\u3067\u3059\u3002<\/p>\n

    \n
  1. \u5404\u30a2\u30df\u30ce\u9178\u6b8b\u57fa\u306bhydropathy index\u3092\u5272\u308a\u632f\u308b\u3002<\/li>\n
  2. i\u756a\u76ee\u306e\u30a2\u30df\u30ce\u9178\u6b8b\u57fa\u306e\u524d\u5f8c\uff13\u6b8b\u57fa\uff08i-3\u304b\u3089i+3\u307e\u3067\uff09\u306ehydropathy index\u306e\u5e73\u5747\u3092\u6c42\u3081\u3001\u305d\u306e\u5024\u3092i\u756a\u76ee\u306e\u30a2\u30df\u30ce\u9178\u6b8b\u57fa\u306e\u758e\u6c34\u6027\u3068\u3059\u308b\u3002<\/li>\n
  3. \u5404\u30a2\u30df\u30ce\u9178\u6b8b\u57fa\u306e\u758e\u6c34\u6027\u304c-0.4\u4ee5\u4e0a\u306e\u5834\u5408\u3001\u305d\u306e\u6b8b\u57fa\u306f\u758e\u6c34\u7684\u306a\u9818\u57df\u3092\u4f5c\u308b\u5019\u88dc\u3068\u3059\u308b\u3002<\/li>\n
  4. \u819c\u8cab\u901a\u30d8\u30ea\u30c3\u30af\u30b9\u3092\u5f62\u6210\u3067\u304d\u308b\u6b8b\u57fa\u6570\u4ee5\u4e0a\u306b\u758e\u6c34\u7684\u306a\u9818\u57df\u304c\u5b58\u5728\u3059\u308b\u5834\u5408\u306f\u3001\u305d\u306e\u90e8\u5206\u304c\u819c\u8cab\u901a\u90e8\u4f4d\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3002<\/li>\n<\/ol>\n

    \u4ee5\u4e0a\u306e\u8003\u3048\u65b9\u306b\u5f93\u3063\u3066\u3001FASTA\u5f62\u5f0f\u306e\u30a2\u30df\u30ce\u9178\u914d\u5217\u30c7\u30fc\u30bf\u3092\u8aad\u307f\u8fbc\u3093\u3067\u3001hydropathy plot\u3092\u8868\u793a\u3059\u308b\u30d7\u30ed\u30b0\u30e9\u30e0\u3092\u4f5c\u6210\u3057\u3066\u307f\u307e\u3057\u3087\u3046\u3002<\/p>\n

    \u307e\u305a\u306f\u3001FASTA\u5f62\u5f0f\u3092\u8aad\u307f\u8fbc\u3080\u95a2\u6570\u3092\u4f5c\u308a\u307e\u3057\u3087\u3046\u3002\u3053\u306e\u95a2\u6570\u306b\u6e21\u3059\u5f15\u6570\u306f\u3001FASTA\u5f62\u5f0f\u306e\u30c7\u30fc\u30bf\u304c\u5165\u3063\u305f\u30d5\u30a1\u30a4\u30eb\u540d\u3068\u30a2\u30df\u30ce\u9178\u914d\u5217\u3092\u683c\u7d0d\u3059\u308bchar\u578b\u306e\u914d\u5217\u3067\u3059\u3002\u3053\u306e\u95a2\u6570\u306e\u8fd4\u308a\u5024\u306f\u3001\u8aad\u307f\u8fbc\u3093\u3060\u30a2\u30df\u30ce\u9178\u914d\u5217\u306e\u9577\u3055\u3068\u3059\u308b\u3068\u4fbf\u5229\u3067\u3059\u3002<\/p>\n

    \r\nint  ReadFASTA(char *file, char seq[])\r\n{\r\n    int    len = 0;\r\n    int    flag = 0;\r\n    char   amino;\r\n    FILE  *fp;\r\n\r\n    if ((fp = fopen(file, "r")) == NULL) {\r\n        fprintf(stderr, "ReadFASTA(): Cannot find %s\\n", file);\r\n        exit(1);\r\n    }\r\n\r\n    while ((amino = fgetc(fp)) != EOF) {\r\n        if (amino == '>') {\r\n            flag = 1;\r\n        } else if (flag == 1 && amino == '\\n') {\r\n            flag = 0;\r\n        }\r\n\r\n        if (flag == 0 && amino != '\\n' && amino != ' ') {\r\n            seq[len++] = amino;\r\n        }\r\n    }\r\n    seq[len] = '\0';\r\n\r\n    return len;\r\n}\r\n<\/pre>\n
    8\u884c\u76ee\u304b\u308911\u884c\u76ee\u3067FASTA\u5f62\u5f0f\u306e\u30c7\u30fc\u30bf\u304c\u5165\u3063\u305f\u30d5\u30a1\u30a4\u30eb\u3092\u958b\u3044\u3066\u3044\u307e\u3059\u3002\u3053\u3053\u3067\u5c11\u3057\u65b0\u3057\u3044\u90e8\u5206\u306f\u3001\u3082\u3057\u6307\u5b9a\u3055\u308c\u305f\u30d5\u30a1\u30a4\u30eb\u304c\u5b58\u5728\u3057\u306a\u3044\u5834\u5408\u3001\u30a8\u30e9\u30fc\u51fa\u529b\u3092\u3057\u3066\u30d7\u30ed\u30b0\u30e9\u30e0\u3092\u7d42\u4e86\u3055\u305b\u308b\u3068\u3053\u308d\u3067\u3059\u3002fopen()\u95a2\u6570\u306f\u3001\u30d5\u30a1\u30a4\u30eb\u304c\u958b\u3051\u306a\u3044\u5834\u5408\"NULL\"\u3092\u8fd4\u3057\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u30018\u884c\u76ee\u306b\u304a\u3044\u3066FILE\u30dd\u30a4\u30f3\u30bf\u3067\u3042\u308bfp\u306bNULL\u304c\u4ee3\u5165\u3055\u308c\u305f\u3089\u30019\u884c\u76ee\u306810\u884c\u76ee\u3092\u5b9f\u884c\u3057\u307e\u3059\u30029\u884c\u76ee\u306efprintf()\u95a2\u6570\u306f\u3001\u4f7f\u3044\u65b9\u306fprintf()\u95a2\u6570\u3068\u307b\u307c\u540c\u3058\u3067\u3059\u304c\u3001\uff11\u3064\u76ee\u306e\u5f15\u6570\u306b\u3069\u3053\u306b\u51fa\u529b\u3059\u308b\u304b\u3092\u6307\u5b9a\u3057\u307e\u3059\u30028\u884c\u76ee\u306e\u5834\u5408\u306f\u30a8\u30e9\u30fc\u51fa\u529b\u3092\u3057\u305f\u3044\u306e\u3067\u3001\"stderr\"\u3092\u6307\u5b9a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n
    13\u884c\u76ee\u304b\u308924\u884c\u76ee\u304c\u30d5\u30a1\u30a4\u30eb\u304b\u3089FASTA\u5f62\u5f0f\u3092\u8aad\u307f\u8fbc\u3080\u672c\u4f53\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n
    \u3053\u306e\u90e8\u5206\u3067\u4f7f\u308f\u308c\u3066\u3044\u308b\u5909\u6570\u306e\u8aac\u660e\u3092\u3057\u307e\u3059\u3002amino\u306f\u3001\u30d5\u30a1\u30a4\u30eb\u306b\u7d0d\u3081\u3089\u308c\u3066\u3044\u308b\u6587\u5b57\u3092\uff11\u3064\u3092\u3044\u308c\u308b\u5909\u6570\u3067\u3059\u3002len\u306f\u3001\u8aad\u307f\u8fbc\u3093\u3060\u30a2\u30df\u30ce\u9178\u914d\u5217\u306e\u9577\u3055\u3092\u793a\u3057\u307e\u3059\u3002flag\u306f\u3001FASTA\u5f62\u5f0f\u306e\u30d8\u30c3\u30c0\u30fc\u884c\uff08>\u3067\u59cb\u307e\u308b\u884c\uff09\u3092\u8aad\u307f\u8fbc\u3093\u3067\u3044\u308b\u3068\u3053\u308d\u304b\u3069\u3046\u304b\u3092\u5224\u5b9a\u3059\u308b\u5909\u6570\u3067\u30011\u3060\u3063\u305f\u3089\u30d8\u30c3\u30c0\u30fc\u884c\u3092\u8aad\u307f\u8fbc\u3093\u3067\u304a\u308a\u30010\u3060\u3063\u305f\u3089\u305d\u308c\u4ee5\u5916\u3092\u8aad\u307f\u8fbc\u3093\u3067\u3044\u308b\u3053\u3068\u3092\u793a\u3057\u307e\u3059\u3002<\/p>\n
    13\u884c\u76ee\u306b\u3042\u308bfgetc()\u95a2\u6570\u306f\u3001\u30d5\u30a1\u30a4\u30eb\u304b\u3089\u6587\u5b57\u3092\uff11\u3064\u3060\u3051\u8aad\u307f\u8fbc\u307f\u307e\u3059\u3002\u3082\u3057\u30d5\u30a1\u30a4\u30eb\u306e\u6700\u5f8c\u306b\u6765\u305f\u3089fgetc()\u95a2\u6570\u306f\"EOF\"\u3092\u8fd4\u3057\u307e\u3059\u3002\u3088\u3063\u3066\u300113\u884c\u76ee\u3092\u8aad\u307f\u4e0b\u3059\u3068\u3001\u300c\u30d5\u30a1\u30a4\u30eb\u306e\u4e2d\u8eab\u3092\u4e00\u6587\u5b57\u305a\u3064\u8aad\u307f\u8fbc\u3093\u3067amino\u306b\u5165\u308c\u308b\u3053\u3068\u3092\u3001\u30d5\u30a1\u30a4\u30eb\u306e\u6700\u5f8c\u307e\u3067\u7e70\u308a\u8fd4\u3057\u306a\u3055\u3044\u300d\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n
    14\u884c\u76ee\u304b\u308918\u884c\u76ee\u306f\u3001\u30d8\u30c3\u30c0\u30fc\u884c\u304b\u3069\u3046\u304b\u3092\u5224\u5b9a\u3057\u3066flag\u5909\u6570\u30921\u306b\u5909\u3048\u308b\u3068\u3053\u308d\u3067\u3059\u3002<\/p>\n
    20\u884c\u76ee\u304b\u308922\u884c\u76ee\u306f\u3001\u8aad\u307f\u8fbc\u3093\u3060\u6587\u5b57\u304c\u30d8\u30c3\u30c0\u30fc\u884c\u306e\u3082\u306e\u3067\u306f\u306a\u304f\u3001\u304b\u3064\u3001\u6539\u884c\u3084\u7a7a\u767d\u3067\u306a\u3044\u5834\u5408\u306b\u3001\u914d\u5217seq[]\u306elen\u756a\u76ee\u306bamino\u3092\u4ee3\u5165\u3057\u307e\u3059\u3002\u4ee3\u5165\u3057\u7d42\u3048\u305f\u3089len\u306b1\u3092\u8db3\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n
    24\u884c\u76ee\u3067\u306f\u3001\u6587\u5b57\u5217\u306e\u6700\u5f8c\u306b\u6587\u5b57\u5217\u306e\u7d42\u308f\u308a\u306e\u5370\u3067\u3042\u308b'\\0'\u3092\u4ee3\u5165\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n
    26\u884c\u76ee\u3067\u3053\u306e\u95a2\u6570\u306e\u8fd4\u308a\u5024\u3067\u3042\u308b\u8aad\u307f\u8fbc\u3093\u3060\u30a2\u30df\u30ce\u9178\u914d\u5217\u306e\u9577\u3055\u3092\u8fd4\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n
    \u6b21\u306f\u3001\u8aad\u307f\u8fbc\u3093\u3060\u30a2\u30df\u30ce\u9178\u914d\u5217\u306e\u30a2\u30df\u30ce\u9178\u6b8b\u57fa\u305d\u308c\u305e\u308c\u306bhydropathy index\u3092\u5272\u308a\u632f\u308b\u95a2\u6570\u3092\u4f5c\u308a\u307e\u3059\u3002\u8003\u3048\u65b9\u306e1.\u306b\u3042\u305f\u308b\u95a2\u6570\u3067\u3059\u3002\u3053\u306e\u95a2\u6570\u306e\u5f15\u6570\u306f\u3001\u30a2\u30df\u30ce\u9178\u914d\u5217\u306e\u9577\u3055\u3001\u30a2\u30df\u30ce\u9178\u914d\u5217\u304c\u5165\u3063\u305f\u914d\u5217\u3001\u5272\u308a\u632f\u308bhydropathy index\u3092\u5165\u308c\u308b\u914d\u5217\u3068\u3057\u307e\u3059\u3002\u3053\u306e\u95a2\u6570\u304b\u3089\u7279\u306b\u8fd4\u308a\u5024\u306f\u5fc5\u8981\u3068\u3057\u306a\u3044\u306e\u3067\u3001void\u578b\u306e\u95a2\u6570\u3068\u3057\u307e\u3057\u3087\u3046\u3002void\u578b\u306e\u95a2\u6570\u3068\u306f\u3001\u8fd4\u308a\u5024\u3092\u8fd4\u3055\u306a\u3044\u95a2\u6570\u306e\u3053\u3068\u3067\u3059\u3002<\/p>\n
    \r\nvoid  AssignHydropathyIndex(int len, char seq[], float index[])\r\n{\r\n    int   i, j;\r\n    char  amino[] = "IVLFCMAGTSWYPHEQDNKR";\r\n    float HI[] = {  4.5,  4.2,  3.8,  2.8,  2.5,\r\n                    1.9,  1.8, -0.4, -0.7, -0.8,\r\n                   -0.9, -1.3, -1.6, -3.2, -3.5,\r\n                   -3.5, -3.5, -3.5, -3.9, -4.5 };\r\n\r\n    for (i = 0; i < len; i++) {\r\n        for (j = 0; j < 20; j++) {\r\n            if (seq[i] == amino[j]) {\r\n                index[i] = HI[j];\r\n                break;\r\n            }\r\n        }\r\n    }\r\n}\r\n<\/pre>\n
    4\u884c\u76ee\u3067\u306f20\u7a2e\u985e\u306e\u30a2\u30df\u30ce\u9178\u3067amino[]\u3068\u3044\u3046\u914d\u5217\u3092\u521d\u671f\u5316\u3057\u3066\u3044\u307e\u3059\u30025\u884c\u76ee\u304b\u30898\u884c\u76ee\u3067\u306f\u30014\u884c\u76ee\u3067\u521d\u671f\u5316\u3057\u305f\u30a2\u30df\u30ce\u9178\u306e\u9806\u756a\u3067\u3001HI[]\u3068\u3044\u3046float\u914d\u5217\u3092hydropathy index\u306b\u3088\u308a\u521d\u671f\u5316\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n
    10\u304b\u308917\u884c\u76ee\u306f\u3001\u3053\u308c\u307e\u3067\u306b\u3082\u4f55\u5ea6\u304b\u51fa\u3066\u304d\u305f\u5f62\u3067\u3059\u3002\u3053\u3053\u306e\u90e8\u5206\u3067\u3001\u5404\u30a2\u30df\u30ce\u9178\u306b\u5bfe\u5fdc\u3059\u308bhydropathy index\u3092index[]\u3068\u3044\u3046float\u914d\u5217\u306b\u5165\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n
    \u6b21\u306f\u3001\u8003\u3048\u65b9\u306e2.\u306b\u3042\u305f\u308b\u95a2\u6570\u3092\u4f5c\u308a\u307e\u3059\u3002\u3064\u307e\u308a\u3001i\u756a\u76ee\u306e\u30a2\u30df\u30ce\u9178\u6b8b\u57fa\u306e\u524d\u5f8c\uff13\u6b8b\u57fa\uff08i-3\u304b\u3089i+3\u307e\u3067\uff09\u306ehydropathy index\u306e\u5e73\u5747\u3092\u6c42\u3081\u3001\u305d\u306e\u5024\u3092i\u756a\u76ee\u306e\u30a2\u30df\u30ce\u9178\u6b8b\u57fa\u306e\u758e\u6c34\u6027\u3068\u3059\u308b\u95a2\u6570\u3067\u3059\u3002\u3053\u306e\u95a2\u6570\u306e\u5f15\u6570\u306f\u3001\u30a2\u30df\u30ce\u9178\u914d\u5217\u306e\u9577\u3055\u3001\u5272\u308a\u5f53\u3066\u3089\u308c\u305fhydropathy index\u304c\u5165\u3063\u305ffloat\u914d\u5217\u3001hydropathy index\u306e\u5e73\u5747\u3092\u5165\u308c\u308bfloat\u914d\u5217\u3068\u306a\u308a\u307e\u3059\u3002\u3053\u306e\u95a2\u6570\u3067\u306f\u7279\u306b\u5024\u3092\u8fd4\u3055\u306a\u3044\u305f\u3081\u3001void\u95a2\u6570\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n
    \r\nvoid  CalcHydropathy(int len, float index[], float hydropathy[])\r\n{\r\n    int   i, j;\r\n\r\n    for (i = 3; i < len-3; i++) {\r\n        hydropathy[i] = 0.0;\r\n        for (j = -3; j <= 3; j++) {\r\n            hydropathy[i] += index[i+j];\r\n        }\r\n        hydropathy[i] \/= 7.0;\r\n    }\r\n}\r\n<\/pre>\n
    2.\u306e\u8003\u3048\u65b9\u3067\u3061\u3087\u3063\u3068\u3057\u305f\u554f\u984c\u3068\u306a\u308b\u306e\u306f\u3001\u524d\u5f8c\uff13\u6b8b\u57fa\u306ehydropathy index\u304c\u5fc5\u8981\u3068\u306a\u308b\u305f\u3081\u306bN\u672b\u7aef\u306e\uff13\u6b8b\u57fa\u3068C\u672b\u7aef\u306e\uff13\u6b8b\u57fa\u306b\u306f\u5e73\u5747hydropathy index\u3092\u6c42\u3081\u3089\u308c\u306a\u3044\u3053\u3068\u3067\u3059\u3002\u305d\u3053\u3067\u3053\u306e\u30d7\u30ed\u30b0\u30e9\u30e0\u3067\u306f\u3001N\u672b\u7aef\u306e\uff13\u6b8b\u57fa\u3068C\u672b\u7aef\u306e\uff13\u6b8b\u57fa\u306f\u8a08\u7b97\u3057\u306a\u3044\u3088\u3046\u306b\u3057\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u5e73\u5747\u5024\u3092\u8a08\u7b97\u3059\u308b\u306e\u306b\u3001\u3044\u3061\u3044\u3061i-3\u756a\u76ee\u3001i-2\u756a\u76ee\u3001...\u3001i+2\u756a\u76ee\u3001i+3\u756a\u76ee\u306e\u30a2\u30df\u30ce\u9178\u6b8b\u57fa\u306ehydropathy index\u3092\u66f8\u304d\u51fa\u3057\u3066\u5408\u8a08\u3059\u308b\u306e\u3067\u306f\u306a\u304f\u3001for\u6587\u3092\u4f7f\u3063\u3066\u697d\u3092\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n
    \u6b21\u306e\u95a2\u6570\u306f\u3001\u7d50\u679c\u306e\u51fa\u529b\u3092\u3059\u308b\u95a2\u6570\u3067\u3059\u3002\u3053\u306e\u95a2\u6570\u306e\u5f15\u6570\u306f\u3001\u30a2\u30df\u30ce\u9178\u914d\u5217\u306e\u9577\u3055\u3001\u30a2\u30df\u30ce\u9178\u914d\u5217\u3092\u5165\u308c\u305fchar\u914d\u5217\u3001\u5e73\u5747hydropathy index\u3092\u5165\u308c\u305ffloat\u914d\u5217\u3067\u3059\u3002\u3053\u306e\u95a2\u6570\u3082\u7279\u306b\u5024\u3092\u8fd4\u3055\u306a\u3044\u306e\u3067void\u95a2\u6570\u3067\u3059\u3002<\/p>\n
    \r\nvoid PrintHydropathy(int len, char seq[], float hydropathy[])\r\n{\r\n    int   i;\r\n\r\n    for (i = 0; i < len; i++) {\r\n        printf("%3d  %c  %5.1f  ", i+1, seq[i], hydropathy[i]);\r\n        if (hydropathy[i] >= -0.4) {\r\n            printf("*");\r\n        } else {\r\n            printf(" ");\r\n        }\r\n        printf("\\n");\r\n    }\r\n}\r\n<\/pre>\n
    \u3053\u306e\u95a2\u6570\u3067\u306f\u7279\u306b\u76ee\u65b0\u3057\u3044\u3053\u3068\u306f\u3057\u3066\u3044\u307e\u305b\u3093\u3002\u8003\u3048\u65b93.\u306b\u7fd2\u3063\u3066\u3001\u5e73\u5747hydropathy index\u304c-0.4\u4ee5\u4e0a\u306e\u5834\u5408\u306b\u5370\uff08\u3053\u306e\u5834\u5408\u306f*\uff09\u3092\u8868\u793a\u3059\u308b\u3088\u3046\u306b\u3057\u3066\u3044\u308b\u3060\u3051\u3067\u3059\u3002<\/p>\n
    \u6700\u5f8c\u306f\u3001\u3053\u308c\u307e\u3067\u306e\u95a2\u6570\u3092\u547c\u3073\u51fa\u3059main()\u95a2\u6570\u3067\u3059\u3002\u30b3\u30de\u30f3\u30c9\u30e9\u30a4\u30f3\u304b\u3089\u306e\u5f15\u6570\u3067FASTA\u5f62\u5f0f\u306e\u30a2\u30df\u30ce\u9178\u914d\u5217\u304c\u5165\u3063\u305f\u30d5\u30a1\u30a4\u30eb\u540d\u3092\u6307\u5b9a\u3059\u308b\u3088\u3046\u306b\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n
    \r\n#include <stdio.h>\r\n#include <string.h>\r\n#include <stdlib.h>\r\n\r\n#define MAXLEN      2000\r\n\r\nint main(int argc, char *argv[]) \r\n{\r\n    int   seqLen;\r\n    char  seq[MAXLEN];\r\n    float index[MAXLEN];\r\n    float hydropathy[MAXLEN];\r\n\r\n    int   ReadFASTA(char *, char []);\r\n    void  AssignHydropathyIndex(int, char [], float []);\r\n    void  CalcHydropathy(int, float [], float []);\r\n    void  PrintHydropathy(int, char [], float []);\r\n    \r\n    if (argc != 2) {\r\n        fprintf(stderr, "%s  FASTA_FILE\\n", argv[0]);\r\n        exit(1);\r\n    }\r\n\r\n    seqLen = ReadFASTA(argv[1], seq);\r\n    AssignHydropathyIndex(seqLen, seq, index);\r\n    CalcHydropathy(seqLen, index, hydropathy);\r\n    PrintHydropathy(seqLen, seq, hydropathy);\r\n\r\n    return 0;\r\n}\r\n<\/pre>\n
    1\u884c\u76ee\u304b\u30895\u884c\u76ee\u307e\u3067\u306fheader\u30d5\u30a1\u30a4\u30eb\u306e\u6307\u5b9a\u3092\u3057\u3066\u3044\u308b\u3068\u3053\u308d\u3067\u3059\u3002\u3053\u306e\u5834\u5408\u306f\u4fbf\u5b9c\u4e0amain()\u95a2\u6570\u3068\u4e00\u7dd2\u306b\u66f8\u3044\u3066\u3044\u307e\u3059\u304c\u3001\u5b9f\u969b\u306e\u30bd\u30fc\u30b9\u30b3\u30fc\u30c9\u3067\u306f\u30d5\u30a1\u30a4\u30eb\u306e\u5148\u982d\u306b\u66f8\u304f\u3088\u3046\u306b\u3057\u3066\u4e0b\u3055\u3044\u3002<\/p>\n
    9\u884c\u76ee\u304b\u308912\u884c\u76ee\u3067\u3001\u5909\u6570\u3092\u5ba3\u8a00\u3057\u3066\u3044\u307e\u3059\u3002MAXLEN\u306f#define\u306b\u3088\u308a2000\u306b\u7f6e\u304d\u63db\u3048\u3089\u308c\u307e\u3059\u3002\u3064\u307e\u308a\u3001\u3053\u306e\u30d7\u30ed\u30b0\u30e9\u30e0\u3067\u306f\u8aad\u307f\u8fbc\u3081\u308b\u30a2\u30df\u30ce\u9178\u914d\u5217\u306e\u6700\u5927\u6b8b\u57fa\u9577\u304c2000\u672a\u6e80\u3068\u3044\u3046\u3053\u3068\u3092\u610f\u5473\u3057\u307e\u3059\u3002<\/p>\n
    14\u884c\u76ee\u304b\u308917\u884c\u76ee\u306f\u95a2\u6570\u306e\u5ba3\u8a00\u3092\u3057\u3066\u3044\u307e\u3059\u3002\u5ba3\u8a00\u6587\u3067\u306f\u3001\u5f15\u6570\u304c\u3069\u3046\u3044\u3046\u5909\u6570\u304b\u304c\u308f\u304b\u308c\u3070\u3044\u3044\u306e\u3067\u3001\u5909\u6570\u540d\u306f\u7701\u7565\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n
    19\u884c\u76ee\u304b\u308922\u884c\u76ee\u306f\u3001\u5f15\u6570\u3092\uff11\u3064\u6307\u5b9a\u3057\u306a\u3044\u3068\u4f7f\u3044\u65b9\u3092\u8868\u793a\u3057\u3066\u7d42\u4e86\u3055\u305b\u308b\u90e8\u5206\u3067\u3059\u300224\u884c\u76ee\u304b\u308927\u884c\u76ee\u306f\u9806\u756a\u306b\u95a2\u6570\u3092\u547c\u3073\u51fa\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n
    \u4ee5\u4e0a\u3067\u3001\u6700\u4f4e\u9650\u5fc5\u8981\u306a\u30bd\u30fc\u30b9\u30b3\u30fc\u30c9\u306f\u3059\u3079\u3066\u7528\u610f\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3057\u305f\u3002\u3059\u3079\u3066\u3092\u5165\u529b\u3057\u3001hydro.c\u3068\u3067\u3082\u540d\u524d\u3092\u4ed8\u3051\u3066\u30d5\u30a1\u30a4\u30eb\u306b\u4fdd\u5b58\u3057\u3001\u30b3\u30f3\u30d1\u30a4\u30eb\u3057\u307e\u3057\u3087\u3046\u3002\u30b3\u30f3\u30d1\u30a4\u30eb\u3067\u304d\u305f\u3089\u3001\u5b9f\u969b\u306b\u9069\u5f53\u306a\u30a2\u30df\u30ce\u9178\u914d\u5217\uff08\u4f8b\u3048\u3070\u3001Swiss-Prot\u30a8\u30f3\u30c8\u30ea\u30fc\u306eOPSD_HUMAN\u3084HBA_HUMAN\u306a\u3069\u3092FASTA\u5f62\u5f0f\u3067\u4fdd\u5b58\u3057\u305f\u30c7\u30fc\u30bf\u306a\u3069\uff09\u3092\u7528\u610f\u3057\u3066\u30d7\u30ed\u30b0\u30e9\u30e0\u3092\u5b9f\u884c\u3057\u3066\u307f\u307e\u3057\u3087\u3046\u3002<\/p>\n
    \u7df4\u7fd2\u554f\u984c<\/h2>\n
      \n
    1. \u8003\u3048\u65b9\u306e4.\u306b\u5f93\u3063\u3066\u3001\u819c\u8cab\u901a\u30d8\u30ea\u30c3\u30af\u30b9\u3068\u4e88\u6e2c\u3055\u308c\u308b\u30a2\u30df\u30ce\u9178\u6b8b\u57fa\u306b\u5370\u3092\u4ed8\u3051\u308b\u3088\u3046\u306b\u3057\u306a\u3055\u3044\u3002\u3053\u3053\u3067\u3001\u8102\u8cea\u4e8c\u91cd\u819c\u3092\u8cab\u901a\u3059\u308b\u306e\u306b\u5fc5\u8981\u306a\u6700\u4f4e\u30a2\u30df\u30ce\u9178\u6b8b\u57fa\u9577\u306f20\u6b8b\u57fa\u3068\u3059\u308b\u3002<\/li>\n
    2. Swiss-Prot\u5f62\u5f0f\u306e\u30a2\u30df\u30ce\u9178\u914d\u5217\u30c7\u30fc\u30bf\u3092\u8aad\u307f\u8fbc\u3093\u3067hydropathy plot\u3092\u6c42\u3081\u308b\u30d7\u30ed\u30b0\u30e9\u30e0\u3092\u4f5c\u6210\u3057\u306a\u3055\u3044\u3002<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"
      hydropathy plot \u4eca\u56de\u4f5c\u6210\u3059\u308b\u30d7\u30ed\u30b0\u30e9\u30e0\u306f\u3001\u819c\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u819c\u8cab\u901a\u90e8\u4f4d\u3092\u4e88\u6e2c\u3059\u308b\u305f\u3081\u306ehydropathy plot\u3067\u3059\u3002 \u819c\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u304a\u3044\u3066\u819c\u306b\u57cb\u307e\u3063\u3066\u3044\u308b\u90e8\u4f4d\u306f\u3001\u305d\u306e\u758e\u6c34\u7684\u306a\u74b0\u5883\u306b\u5408\u308f\u305b\u3066\u758e\u6c34\u6027\u306e\u9ad8\u3044\u30a2 […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":96,"menu_order":9,"comment_status":"closed","ping_status":"closed","template":"","meta":{"vkexunit_cta_each_option":"","footnotes":""},"class_list":["post-157","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/b-lab.nagahama-i-bio.ac.jp\/~m_shionyu\/index.php?rest_route=\/wp\/v2\/pages\/157","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/b-lab.nagahama-i-bio.ac.jp\/~m_shionyu\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/b-lab.nagahama-i-bio.ac.jp\/~m_shionyu\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/b-lab.nagahama-i-bio.ac.jp\/~m_shionyu\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/b-lab.nagahama-i-bio.ac.jp\/~m_shionyu\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=157"}],"version-history":[{"count":2,"href":"https:\/\/b-lab.nagahama-i-bio.ac.jp\/~m_shionyu\/index.php?rest_route=\/wp\/v2\/pages\/157\/revisions"}],"predecessor-version":[{"id":176,"href":"https:\/\/b-lab.nagahama-i-bio.ac.jp\/~m_shionyu\/index.php?rest_route=\/wp\/v2\/pages\/157\/revisions\/176"}],"up":[{"embeddable":true,"href":"https:\/\/b-lab.nagahama-i-bio.ac.jp\/~m_shionyu\/index.php?rest_route=\/wp\/v2\/pages\/96"}],"wp:attachment":[{"href":"https:\/\/b-lab.nagahama-i-bio.ac.jp\/~m_shionyu\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=157"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}